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038597 Rabbit Anti-MRPL41, NT (MRPL41, BMRP, MRPL27, RPML27, 39S ribosomal protein L41, mitochondrial, 39S ribosomal protein L27 homolog, Bcl-2-interacting mitochondrial ribosomal protein L41, Cell proliferation-inducing gene 3 protein, MRP-L27 homolog)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q8IXM3
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_115866.1
Gene ID
64975
Gene #
MRPL41
Shipping Temp
Blue Ice
Storage Temp
-20°C
MRPL41, BMRP, MRPL27, RPML27, 39S ribosomal protein L41, mitochondrial, 39S ribosomal protein L27 homolog, Bcl-2-interacting mitochondrial ribosomal protein L41, Cell proliferation-inducing gene 3 protein, MRP-L27 homolog

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MRPL41 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human MRPL41.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Kim, M.J., et al. Biochem. Biophys. Res. Commun. 338(2):1179-1184(2005)|Yoo, Y.A., et al. Mol. Cell. Biol. 25(15):6603-6616(2005)|Chintharlapalli, S.R., et al. J. Cell. Biochem. 94(3):611-626(2005)|Humphray, S.J., et al. Nature 429(6990):369-374(2004)|Zhang, Z., et al. Genomics 81(5):468-480(2003)
USBio References
No references available
Conjugates
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