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You are here:Home » Antibodies » Abs to Inflammasomes » Anti -NAL11, ID (NLRP11, NALP11, NOD17, PAN10, PYPAF6, NACHT, LRR and PYD domains-containing protein 11, Nucleotide-binding oligomerization domain protein 17, PAAD-and NACHT domain-containing protein 10, PYRIN-containing APAF1-like protein 6) (Biotin)

Anti -NAL11, ID (NLRP11, NALP11, NOD17, PAN10, PYPAF6, NACHT, LRR and PYD
domains-containing protein 11, Nucleotide-binding oligomerization domain protein 17,
PAAD-and NACHT domain-containing protein 10, PYRIN-containing APAF1-like protein 6)
(Biotin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH FC
NAL11 are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NAL11 are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes.
Catalog #038780-Biotin
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Biotin.
PurityPurified by Protein A affinity chromatography.
ImmunogenNAL11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467~497 amino acids from the Central region of human NAL11.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesNLRP11, NALP11, NOD17, PAN10, PYPAF6, NACHT, LRR and PYD domains-containing protein 11, Nucleotide-binding oligomerization domain protein 17, PAAD-and NACHT domain-containing protein 10, PYRIN-containing APAF1-like protein 6


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