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You are here:Home » Antibodies » Abs to Nephrin » Anti -Nephrin (Y1210) (NPHS1, NPHN, Nephrin, Renal glomerulus-specific cell adhesion receptor) (Azide free) (HRP)

Anti -Nephrin (Y1210) (NPHS1, NPHN, Nephrin, Renal glomerulus-specific cell adhesion
receptor) (Azide free) (HRP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B FC
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Catalog #038894-HRP
ApplicationsSuitable for use in Western Blot, Flow Cytometry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Labeled with horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free). Conjugated to HRP.
PurityPurified by Protein A affinity chromatography.
ImmunogenNephrin (Y1210) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1198-1227 amino acids from human Nephrin.
SpecificityHuman, mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesNPHS1, NPHN, Nephrin, Renal glomerulus-specific cell adhesion receptor


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