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You are here:Home » Antibodies » Abs to Nephrin » Anti -Nephrin, phosphorylated (Y1193) (NPHS1, NPHN, Nephrin, Renal glomerulus-specific cell adhesion receptor)

Anti -Nephrin, phosphorylated (Y1193) (NPHS1, NPHN, Nephrin, Renal glomerulus-specific
cell adhesion receptor)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E Gel
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Catalog #038896
ApplicationsSuitable for use in Dot Blot, ELISA
Recommended DilutionELISA: 1:1,000
Dot blot 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenPhospho-Nephrin (Y1193) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding Y1193 of human Nephrin.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesNPHS1, NPHN, Nephrin, Renal glomerulus-specific cell adhesion receptor


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