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039006 Rabbit Anti-NKX6-1, CT (NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P78426
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_006159.2
Gene ID
4825
Gene #
NKX6-1
Shipping Temp
Blue Ice
Storage Temp
-20°C
NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A

In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM].

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
NKX6-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-312 amino acids from the C-terminal region of human NKX6-1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Donelan, W., et al. J. Biol. Chem. 285(16):12181-12189(2010)|Zhu, S., et al. Dig. Dis. Sci. 54(5):996-1002(2009)|Schisler, J.C., et al. Mol. Cell. Biol. 28(10):3465-3476(2008)|Yokoi, N., et al. Diabetes 55(8):2379-2386(2006)|Hori, Y., et al. PLoS Med. 2 (4), E103 (2005) :
USBio References
No references available
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