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039076 Rabbit Anti-NOXO1, ID (NOXO1, P41NOX, SH3PXD5, NADPH oxidase organizer 1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1, SH3 and PX domain-containing protein 5)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q8NFA2
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_653204.1; NP_751907.1
Gene ID
124056
Gene #
NOXO1
Shipping Temp
Blue Ice
Storage Temp
-20°C
NOXO1, P41NOX, SH3PXD5, NADPH oxidase organizer 1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1, SH3 and PX domain-containing protein 5

NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). NOX organizers, such as NOXO1, target NOX activators (see NOXA1; MIM 611255) to NOX and also target NOX to different subcellular compartments (Opitz et al., 2007 [PubMed 17189823]).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
NOXO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of human NOXO1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Dutta, S., et al. PLoS ONE 5 (5), E10478 (2010) :|Opitz, N., et al. Free Radic. Biol. Med. 42(2):175-179(2007)|Yamamoto, A., et al. Biochem. Biophys. Res. Commun. 352(2):560-565(2007)|Takeya, R., et al. FEBS J. 273(16):3663-3677(2006)|Cheng, G., et al. J. Biol. Chem. 281(26):17718-17726(2006)
USBio References
No references available
Conjugates
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