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039508 Rabbit Anti-ORMDL3, ID (ORMDL3, ORM1-like protein 3)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q8N138
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_644809.1
Gene ID
94103
Gene #
ORMDL3
Shipping Temp
Blue Ice
Storage Temp
-20°C
ORMDL3, ORM1-like protein 3

Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.

Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 53-81 in the central region of human ORMDL3, Swiss/UniProt Accession: Q8N138 Species Sequence Homology: bovine, zebrafish, Xenopus, rat
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human ORMDL3. Species Crossreactivity: mouse
References
1. Fransen, K., et al. Hum. Mol. Genet. 19(17):3482-3488(2010). 2. Liu, X., et al. Nat. Genet. 42(8):658-660(2010). 3. Halapi, E., et al. Eur. J. Hum. Genet. 18(8):902-908(2010). 4. Dobbins, S.E., et al. Int. J. Cancer (2010) . 5. McGovern, D.P., et al. Nat. Genet. 42(4):332-337(2010)
USBio References
No references available
Conjugates
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