PAN2, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q504Q3

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Accession #

NP_055686.3; NP_001120932.1

Gene ID

9924

Gene #

PAN2

Shipping Temp

Blue Ice

Storage Temp

-20°C

PAN2, KIAA0710, USP52, PAB-dependent poly(A)-specific ribonuclease subunit 2, Inactive ubiquitin carboxyl-terminal hydrolase 52

This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants.

Applications

Suitable for use in Western Blot, ELISA

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:100-500

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

PAN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 859-888 amino acids from the C-terminal region of human PAN2.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A affinity chromatography.

Specificity

Human

References

Bailey, S.D., et al. Diabetes Care (2010) In press :|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)|Funakoshi, Y., et al. Genes Dev. 21(23):3135-3148(2007)|Ezzeddine, N., et al. Mol. Cell. Biol. 27(22):7791-7801(2007)|Yamashita, A., et al. Nat. Struct. Mol. Biol. 12(12):1054-1063(2005)

USBio References

No references available

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039634 Rabbit Anti-PAN2, CT (PAN2, KIAA0710, USP52, PAB-dependent poly(A)-specific ribonuclease subunit 2, Inactive ubiquitin carboxyl-terminal hydrolase 52)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

PAN2, KIAA0710, USP52, PAB-dependent poly(A)-specific ribonuclease subunit 2, Inactive ubiquitin carboxyl-terminal hydrolase 52

References

USBio References

Conjugates

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