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You are here:Home » Antibodies » Abs to Enzymes, Phosphodiesterase » Anti -PDE11A, NT (PDE11A, Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, cAMP and cGMP phosphodiesterase 11A)

Anti -PDE11A, NT (PDE11A, Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, cAMP and
cGMP phosphodiesterase 11A)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Catalog #039797
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenPDE11A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-63 amino acids from the N-terminal region of human PDE11A.
SpecificityHuman, mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPDE11A, Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, cAMP and cGMP phosphodiesterase 11A


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