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039807 Rabbit Anti-PDE6C, ID (PDE6C, PDEA2, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', cGMP phosphodiesterase 6C)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P51160
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Accession #
P51160; Q91ZQ1
Gene ID
5146
Gene #
PDE6C
Shipping Temp
Blue Ice
Storage Temp
-20°C
PDE6C, PDEA2, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', cGMP phosphodiesterase 6C

PDE6C is the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa.

Applications
Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended Dilutions
Immunohistochemistry (FFPE): 1:50-1:100 Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 271-300 in the central region of human PDE6C.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography followed by peptide affinity purification.
Specificity
Recognizes human PDE6C. Species Crossreactivity: mouse.
References
1. Muradov, H., et al. J. Biol. Chem. 284(47): 32662-32669 (2009). 2. Chang, B., et al. Proc. Natl. Acad. Sci. U.S.A. 106(46):19581-19586(2009). 3. Thiadens, A.A., et al. Am. J. Hum. Genet. 85(2):240-247 (2009)
USBio References
No references available
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