PDE6D, ID

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Hu Mo

Accession #

O43924; NP_002592.1

Gene ID

5147

Gene #

PDE6D

Shipping Temp

Blue Ice

Storage Temp

-20°C

PDE6D, PDED, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, Protein p17

Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation.

Applications

Suitable for use in Western Blot and ELISA. Other applications have not been tested.

Recommended Dilutions

Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 26-55 in the central region of human PDE6D. Species Sequence Homology: bovine

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A and peptide affinity chromatography

Specificity

Recognizes human PDE6D. Species Crossreactivity: mouse

References

1. Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008). 2. Wilson, S.J., et al. J. Biol. Chem. 281(17):11780-11786(2006). 3. Stelzl, U., et al. Cell 122(6):957-968(2005). 4. Hanzal-Bayer, M., et al. EMBO J. 21(9):2095-2106(2002). 5. Nancy, V., et al. J. Biol. Chem. 277(17):15076-15084(2002)

USBio References

No references available

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039808 Rabbit Anti-PDE6D, ID (PDE6D, PDED, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, Protein p17)

Clone Type

Host

Source

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

PDE6D, PDED, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, Protein p17

References

USBio References

Conjugates

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