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039883 Rabbit Anti-PERP, CT (PERP, KCP1, KRTCAP1, PIGPC1, THW, p53 apoptosis effector related to PMP-22, Keratinocyte-associated protein 1, P53-induced protein PIGPC1, Transmembrane protein THW)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q96FX8
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_071404.2
Gene ID
64065
Gene #
PERP
Shipping Temp
Blue Ice
Storage Temp
-20°C
PERP, KCP1, KRTCAP1, PIGPC1, THW, p53 apoptosis effector related to PMP-22, Keratinocyte-associated protein 1, P53-induced protein PIGPC1, Transmembrane protein THW

Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).

Applications
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 162-191 in the C-terminal region of human PERP.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human PERP.
References
1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 2. Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010) 3. Yarden, R.I., et al. Mol. Carcinog. 49(6):545-555(2010) 4. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) 5. Beaudry, V.G., et al. Am. J. Med. Genet. A 149A (9), 1952-1957 (2009) :
USBio References
No references available
Conjugates
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