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You are here:Home » Antibodies » Abs to Mitochondrial Proteins » Anti -PITRM1, ID (PITRM1, KIAA1104, MP1, Presequence protease, mitochondrial, Pitrilysin metalloproteinase 1)

Anti -PITRM1, ID (PITRM1, KIAA1104, MP1, Presequence protease, mitochondrial, Pitrilysin
metalloproteinase 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.
Catalog #040085
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenPITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 497-526 amino acids from the Central region of human PITRM1.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPITRM1, KIAA1104, MP1, Presequence protease, mitochondrial, Pitrilysin metalloproteinase 1


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