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You are here:Home » Antibodies » Abs to Pleckstrin Homology Proteins » Anti -PLEKHF1, NT (PLEKHF1, APPD, LAPF, ZFYVE15, Pleckstrin homology domain-containing family F member 1, Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains, PH and FYVE domain-containing protein 1, Phafin-1, Zinc finger FYVE domain-c

Anti -PLEKHF1, NT (PLEKHF1, APPD, LAPF, ZFYVE15, Pleckstrin homology domain-containing
family F member 1, Lysosome-associated apoptosis-inducing protein containing PH and FYVE
domains, PH and FYVE domain-containing protein 1, Phafin-1, Zinc finger FYVE domain-c

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Catalog #040158
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenPLEKHF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human PLEKHF1.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPLEKHF1, APPD, LAPF, ZFYVE15, Pleckstrin homology domain-containing family F member 1, Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains, PH and FYVE domain-containing protein 1, Phafin-1, Zinc finger FYVE domain-containing pro


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