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You are here:Home » Antibodies » Abs to Wnt Proteins » Anti -PRICKLE1, CT (PRICKLE1, RILP, Prickle-like protein 1, REST/NRSF-interacting LIM domain protein 1)

Anti -PRICKLE1, CT (PRICKLE1, RILP, Prickle-like protein 1, REST/NRSF-interacting LIM
domain protein 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3.
Catalog #040430
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenPRICKLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 677-704 amino acids selected from the C-terminal region of human PRICKLE1.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPRICKLE1, RILP, Prickle-like protein 1, REST/NRSF-interacting LIM domain protein 1


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