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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc, Ring, Homeobox » Anti -PROX-1 (S514) (PROX1, Prospero Homeobox Protein 1, Homeobox Prospero-like Protein PROX1)

Anti -PROX-1 (S514) (PROX1, Prospero Homeobox Protein 1, Homeobox Prospero-like Protein
PROX1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH FC
Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
Catalog #040484
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications have not been tested.
Recommended DilutionWestern Blot: 1:1000
Immunohistochemistry: 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 492-520 of human PROX1, UniProt Accession #Q92786.
SpecificityRecognizes human PROX1. Species Crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPROX1, Prospero homeobox protein 1, Homeobox prospero-like protein PROX1


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