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You are here:Home » Antibodies » Abs to Proteasomes » Anti -PSMA1, CT (PSMA1, HC2, NU, PROS30, PSC2, Proteasome subunit alpha type-1, 30kD prosomal protein, Macropain subunit C2, Multicatalytic endopeptidase complex subunit C2, Proteasome component C2, Proteasome nu chain) (APC)

Anti -PSMA1, CT (PSMA1, HC2, NU, PROS30, PSC2, Proteasome subunit alpha type-1, 30kD
prosomal protein, Macropain subunit C2, Multicatalytic endopeptidase complex subunit C2,
Proteasome component C2, Proteasome nu chain) (APC)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Catalog #040552-APC
ApplicationsSuitable for use in Western Blot, FLISA
Recommended DilutionFLISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Allophycocyanin (APC).
PurityPurified by Protein A affinity chromatography.
ImmunogenPSMA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 233-262 amino acids from the C-terminal region of human PSMA1.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPSMA1, HC2, NU, PROS30, PSC2, Proteasome subunit alpha type-1, 30kD prosomal protein, Macropain subunit C2, Multicatalytic endopeptidase complex subunit C2, Proteasome component C2, Proteasome nu chain


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