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040907 Rabbit Anti-RBMY1A1, CT (RNA-binding motif protein, Y chromosome, family 1 member A1/C,RBM1, RBM2, YRRM1)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P0DJD3
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_005049.1
Gene ID
5940
Gene #
RBMY1A1
Shipping Temp
Blue Ice
Storage Temp
-20°C
RNA-binding motif protein, Y chromosome, family 1 member A1/C,RBM1, RBM2, YRRM1

This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq].

Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 468-496 in the C-terminal region of human RBMY1A1
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human RBMY1A1
References
1. Dreumont, N., et al. J. Cell. Sci. 123 (PT 1), 40-50 (2010). 2. Liu, Y., et al. PLoS Genet. 5 (11), E1000707 (2009). 3. Lardone, M.C., et al. Mol. Hum. Reprod. 13(10):705-712(2007). 4. Skrisovska, L., et al. EMBO Rep. 8(4):372-379(2007). 5. Lavery, R., et al. Arch. Androl. 53(2):71-73(2007).
USBio References
No references available
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