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041190 Rabbit Anti-RPL11, NT (RPL11, 60S ribosomal protein L11, CLL-associated antigen KW-12)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P62913
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu
Accession #
NP_000966.2
Gene ID
6135
Gene #
RPL11
Shipping Temp
Blue Ice
Storage Temp
-20°C
RPL11, 60S ribosomal protein L11, CLL-associated antigen KW-12

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternative splice variants encoding different isoforms may exist, but they have not been fully characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq].

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1-30 in the N-terminal region of human RPL11. Species sequence homology: bovine, mouse, porcine, rat
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human RPL11.
References
1. Sun, X.X., et al. J. Biol. Chem. 285(33):25812-25821(2010) 2. Konno, Y., et al. Haematologica 95(8):1293-1299(2010) 3. Dai, M.S., et al. J. Biol. Chem. 285(17):12587-12594(2010) 4. Holzel, M., et al. J. Biol. Chem. 285(9):6364-6370(2010) 5. Quarello, P., et al. Haematologica 95(2):206-213(2010)
USBio References
No references available
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