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041263 Rabbit Anti-RPS6KB2 (RPS6KB2, STK14B, Ribosomal protein S6 kinase beta-2, 70kD ribosomal protein S6 kinase 2, S6 kinase-related kinase, Serine/threonine-protein kinase 14B, p70 ribosomal S6 kinase beta)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9UBS0
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
6199
Gene #
RPS6KB2
Shipping Temp
Blue Ice
Storage Temp
-20°C
RPS6KB2, STK14B, Ribosomal protein S6 kinase beta-2, 70kD ribosomal protein S6 kinase 2, S6 kinase-related kinase, Serine/threonine-protein kinase 14B, p70 ribosomal S6 kinase beta

RPS6KB2 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
RPS6KB2 antibody is generated from rabbits immunized with human RPS6KB2 recombinant protein.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).|Lee-Fruman, K.K., et al., Oncogene 18(36):5108-5114 (1999).|Saitoh, M., et al., Biochem. Biophys. Res. Commun. 253(2):470-476 (1998).|Gout, I., et al., J. Biol. Chem. 273(46):30061-30064 (1998).
USBio References
No references available
Conjugates
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