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041278 Rabbit Anti-RRBP1, CT (RRBP1, KIAA1398, Ribosome-binding protein 1, 180kD ribosome receptor homolog, ES/130-related protein, Ribosome receptor protein)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9P2E9
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Hu
Accession #
NP_004578.2
Gene ID
6238
Gene #
RRBP1
Shipping Temp
Blue Ice
Storage Temp
-20°C
RRBP1, KIAA1398, Ribosome-binding protein 1, 180kD ribosome receptor homolog, ES/130-related protein, Ribosome receptor protein

Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome. Alternate splicing results in multiple transcript variants.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa1327-1355 in the C-terminal region of human RRBP1, UniProt Accession #Q9P2E9; NP_004578.2
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human RRBP1 at ~152kD.
References
1. Ueno, T., et al. J. Biol. Chem. 285(39):29941-29950 (2010). 2. Ueno, T., et al. Exp. Cell Res. 316(3):329-340 (2010). 3. Krasnov, G.S., et al. Mol. Biol. (Mosk.) 43(2):348-356 (2009). 4. Benyamini, P., et al. Mol. Biol. Cell 20(2):732-744 (2009). 5. Bai, J.Z., et al. Cell Biol. Int. 32(5):473-483 (2008)
USBio References
No references available
Conjugates
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