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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -SACA1, NT (SPACA1, SAMP32, Sperm acrosome membrane-associated protein 1, Sperm acrosomal membrane-associated protein 32)

Anti -SACA1, NT (SPACA1, SAMP32, Sperm acrosome membrane-associated protein 1, Sperm
acrosomal membrane-associated protein 32)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH FC
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
Catalog #041379
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Flow Cytometry. Other applications have not been tested.
Recommended DilutionWestern Blot: 1:1000
Immunohistochemistry: 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa46-74 from the N-terminal region of human SACA1, conjugated to KLH.
SpecificityRecognizes human SACA1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSPACA1, SAMP32, Sperm acrosome membrane-associated protein 1, Sperm acrosomal membrane-associated protein 32


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