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041454 Rabbit Anti-SCEL, ID (SCEL, Sciellin)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu
Accession #
NP_659001.2; NP_003834.3; O95171
Gene ID
8796
Gene #
SCEL
Shipping Temp
Blue Ice
Storage Temp
-20°C
SCEL, Sciellin

The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined.

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SCEL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-277 amino acids from the Central region of human SCEL.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Pyle, A.L., et al. Cardiovasc. Pathol. 19 (2), E13-E20 (2010) :|Corona, W., et al. Anticancer Res. 24 (3A), 1417-1419 (2004) :|Champliaud, M.F., et al. J. Invest. Dermatol. 121(4):781-785(2003)|Champliaud, M.F., et al. Genomics 70(2):264-268(2000)|Champliaud, M.F., et al. J. Biol. Chem. 273(47):31547-31554(1998)
USBio References
No references available
Conjugates
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