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You are here:Home » Antibodies » Abs to Splicing Factors » Anti -SF3B3, CT (SF3B3, KIAA0017, SAP130, Splicing factor 3B subunit 3, Pre-mRNA-splicing factor SF3b 130kD subunit, STAF130, Spliceosome-associated protein 130)

Anti -SF3B3, CT (SF3B3, KIAA0017, SAP130, Splicing factor 3B subunit 3, Pre-mRNA-splicing
factor SF3b 130kD subunit, STAF130, Spliceosome-associated protein 130)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
Catalog #041615
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSF3B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1053-1082 amino acids from the C-terminal region of human SF3B3.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSF3B3, KIAA0017, SAP130, Splicing factor 3B subunit 3, Pre-mRNA-splicing factor SF3b 130kD subunit, STAF130, Spliceosome-associated protein 130


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