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You are here:Home » Antibodies » Abs to Splicing Factors » Anti -SF3B4, ID (SF3B4, SAP49, Splicing factor 3B subunit 4, Pre-mRNA-splicing factor SF3b 49kD subunit, SF3b50, Spliceosome-associated protein 49)

Anti -SF3B4, ID (SF3B4, SAP49, Splicing factor 3B subunit 4, Pre-mRNA-splicing factor SF3b
49kD subunit, SF3b50, Spliceosome-associated protein 49)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Catalog #041616
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSF3B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-187 amino acids from the Central region of human SF3B4.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSF3B4, SAP49, Splicing factor 3B subunit 4, Pre-mRNA-splicing factor SF3b 49kD subunit, SF3b50, Spliceosome-associated protein 49


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