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You are here:Home » Antibodies » Abs to Adapter Proteins » Anti -Shb, CT (Shb, SH2 domain-containing adapter protein B)

Anti -Shb, CT (Shb, SH2 domain-containing adapter protein B)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells (By similarity).
Catalog #041700
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenMouse Shb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-95 amino acids from the C-terminal region of mouse Shb.
SpecificityHuman, mouse (predicted)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesShb, SH2 domain-containing adapter protein B


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