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041768 Rabbit Anti-SIX6, ID (SIX6, OPTX2, SIX9, Homeobox protein SIX6, Homeodomain protein OPTX2, Optic homeobox 2, Sine oculis homeobox homolog 6)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
O95475; NP_031400.2
Gene ID
4990
Gene #
SIX6
Shipping Temp
Blue Ice
Storage Temp
-20°C
SIX6, OPTX2, SIX9, Homeobox protein SIX6, Homeodomain protein OPTX2, Optic homeobox 2, Sine oculis homeobox homolog 6

The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in eye development. Defects in this gene are a cause of isolated microphthalmia with cataract type 2 (MCOPCT2).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SIX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-124 amino acids from the Central region of human SIX6.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
References
Zhang, X., et al. Mol. Vis. 15, 2911-2918 (2009) :|Ou, Z., et al. Am. J. Med. Genet. A 146A (19), 2480-2489 (2008) :|Hu, S., et al. Biochemistry 47(11):3586-3594(2008)|Aijaz, S., et al. Invest. Ophthalmol. Vis. Sci. 45(11):3871-3876(2004)|Gallardo, M.E., et al. Am. J. Med. Genet. A 129A (1), 92-94 (2004) :
USBio References
No references available
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