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041787 Rabbit Anti-SLC11A2, ID (SLC11A2, DCT1, DMT1, NRAMP2, Natural resistance-associated macrophage protein 2, Divalent cation transporter 1, Divalent metal transporter 1)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P49281
Isotype
IgG
Grade
Affinity Purified
Applications
E IF WB
Crossreactivity
Hu Mo Rt
Accession #
NP_001167598.1; NP_000608.1; P49281
Gene ID
4891
Gene #
SLC11A2
Shipping Temp
Blue Ice
Storage Temp
-20°C
SLC11A2, DCT1, DMT1, NRAMP2, Natural resistance-associated macrophage protein 2, Divalent cation transporter 1, Divalent metal transporter 1

This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications
Suitable for use in Western Blot, Immunofluorescence and ELISA. Optimal dilutions to be determined by the researcher.
Recommended Dilution
Western Blot: 1:1000 Immunofluorescence: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 262-291 in the central region of mouse SLC11A2, UniProt Accession #NP_001167598.1; NP_000608.1; P49281.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human SLC11A2. Species Crossreactivity: mouse and rat
References
1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 2. Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010) 3. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) 4. Tabuchi, M., et al. J. Cell. Sci. 123 (PT 5), 756-766 (2010) 5. Tabuchi, M., et al. Mol. Biol. Cell 13(12):4371-4387(2002)
USBio References
No references available
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