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042149 Rabbit Anti-SOSTDC1, CT (SOSTDC1, USAG1, Sclerostin domain-containing protein 1, Ectodermal BMP inhibitor, Uterine sensitization-associated gene 1 protein)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q6X4U4
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_056279.1
Gene ID
25928
Gene #
SOSTDC1
Shipping Temp
Blue Ice
Storage Temp
-20°C
SOSTDC1, USAG1, Sclerostin domain-containing protein 1, Ectodermal BMP inhibitor, Uterine sensitization-associated gene 1 protein

This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
SOSTDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the C-terminal region of human SOSTDC1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
References
Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :|Ohshima, J., et al. Genes Chromosomes Cancer 48(12):1037-1050(2009)|Blish, K.R., et al. Mol. Biol. Cell 19(2):457-464(2008)|Lamesch, P., et al. Genomics 89(3):307-315(2007)|Yanagita, M. Cytokine Growth Factor Rev. 16(3):309-317(2005)
USBio References
No references available
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