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042238 Rabbit Anti-SPIRE1, CT (SPIRE1, KIAA1135, SPIR1, Protein spire homolog 1)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q08AE8
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001122099.1; NP_001122098.1
Gene ID
56907
Gene #
SPIRE1
Shipping Temp
Blue Ice
Storage Temp
-20°C
SPIRE1, KIAA1135, SPIR1, Protein spire homolog 1

Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).[supplied by OMIM].

Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 664-691 corresponding to the C-terminal region of human SPIRE1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human SPIRE1.
References
1. Rose, J. Phd, et al. Mol. Med. (2010) In press : 2 .Pechlivanis, M., et al. J. Biol. Chem. 284(37):25324-25333(2009), 3. Bosch, M., et al. Mol. Cell 28(4):555-568(2007), 4. Ewing, R.M., et al. Mol. Syst. Biol. 3:89 (2007) : 5. Kerkhoff, E., et al. Curr. Biol. 11(24):1963-1968(2001)
USBio References
No references available
Conjugates
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