TGFBRAP1, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q8WUH2

Isotype

IgG

Grade

Affinity Purified

Applications

E IHC WB

Crossreactivity

Accession #

NP_004248.2; NP_001136093.1

Gene ID

9392

Gene #

TGFBRAP1

Shipping Temp

Blue Ice

Storage Temp

-20°C

TGFBRAP1, Transforming growth factor-beta receptor-associated protein 1

TGFBRAP1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.

Applications

Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications not tested.

Recommended Dilutions

Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 499-528 in the C-terminal region of human TGFBRAP1.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A and peptide affinity chromatography.

Specificity

Recognizes human TGFBRAP1.

References

1. Rose, J. Phd, et al. Mol. Med. (2010). 2. Le Clerc, S., et al. J. Infect. Dis. 200(8):1194-1201(2009). 3. Hwang, Y., et al. Pharmacogenomics 7(5):697-709(2006). 4. Wurthner, J.U., et al. J. Biol. Chem. 276(22):19495-19502(2001). 5. Provost, P., et al. Proc. Natl. Acad. Sci. U.S.A. 96(5):1881-1885(1999)

USBio References

No references available

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042783 Rabbit Anti-TGFBRAP1, CT (TGFBRAP1, Transforming growth factor-beta receptor-associated protein 1)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

TGFBRAP1, Transforming growth factor-beta receptor-associated protein 1

References

USBio References

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