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042854 Rabbit Anti-TIPIN, NT (TIPIN, TIMELESS-interacting protein)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9BVW5
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_060328.2
Gene ID
54962
Gene #
TIPIN
Shipping Temp
Blue Ice
Storage Temp
-20°C
TIPIN, TIMELESS-interacting protein

Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Kemp, M.G., et al. J. Biol. Chem. 285(22):16562-16571(2010)|Leman, A.R., et al. J. Cell. Sci. 123 (PT 5), 660-670 (2010) :|Utge, S.J., et al. PLoS ONE 5 (2), E9259 (2010) :|Unsal-Kacmaz, K., et al. Mol. Cell. Biol. 27(8):3131-3142(2007)|Gotter, A.L., et al. J. Mol. Biol. 366(1):36-52(2007)
USBio References
No references available
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