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You are here:Home » Antibodies » Abs to Transmembrane Proteins » Anti -TM173, CT (TMEM173, ERIS, MITA, STING, Transmembrane protein 173, Endoplasmic reticulum interferon stimulator, Mediator of IRF3 activation, Stimulator of interferon genes protein)

Anti -TM173, CT (TMEM173, ERIS, MITA, STING, Transmembrane protein 173, Endoplasmic
reticulum interferon stimulator, Mediator of IRF3 activation, Stimulator of interferon
genes protein)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B FC
TM173 acts as a facilitator of innate immune signaling. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
Catalog #042892
ApplicationsSuitable for use in Western Blot, Flow Cytometry and ELISA. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs Reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 311-340 in the C-terminal region of human TM173, UniProt Accession #Q86WV6.
SpecificityRecognizes human TM173.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTMEM173, ERIS, MITA, STING, Transmembrane protein 173, Endoplasmic reticulum interferon stimulator, Mediator of IRF3 activation, Stimulator of interferon genes protein


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