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043096 Rabbit Anti-Tnks 2, CT (TNKS2, PARP5B, TANK2, TNKL, Tankyrase-2, ADP-ribosyltransferase diphtheria toxin-like 6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9H2K2
Isotype
IgG
Grade
Purified
Applications
E FC WB
Crossreactivity
Hu Mo
Accession #
NP_079511.1
Gene ID
80351
Gene #
TNKS2
Shipping Temp
Blue Ice
Storage Temp
-20°C
TNKS2, PARP5B, TANK2, TNKL, Tankyrase-2, ADP-ribosyltransferase diphtheria toxin-like 6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein

Tnks 2 may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Tnks 2 has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Tnks 2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1134-1164 amino acids from the C-terminal region of human Tnks 2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation
Specificity
Human, mouse
References
Varadi, V., et al. Eur. J. Cancer 45(17):3008-3016(2009)|Shebzukhov, Y.V., et al. Cancer Immunol. Immunother. 57(6):871-881(2008)|Sidorova, N.N., et al. Biochemistry Mosc. 73(3):289-295(2008)
USBio References
No references available
Conjugates
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