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You are here:Home » Antibodies » Abs to Cardiac Markers » Anti -TNNI3, ID (TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I)

Anti -TNNI3, ID (TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Catalog #043107
ApplicationsSuitable for use in Western Blot. Other applicatiosns not tested.
Recommended DilutionWestern Blot: 1:1,000.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenKLH-conjugated synthetic peptide corresponding to a portion of amino acids within aa 86-114 in the C-terminal region of human TNNI3.
SpecificityPurified by Protein A affinity chromatography followed by peptide affinity purification.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I


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