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You are here:Home » Antibodies » Abs to Topoisomerases » Anti -TOP1, NT (TOP1, DNA topoisomerase 1, DNA topoisomerase I) (Azide free) (HRP)

Anti -TOP1, NT (TOP1, DNA topoisomerase 1, DNA topoisomerase I) (Azide free) (HRP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IF
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Catalog #043127-HRP
ApplicationsSuitable for use in Western Blot and Immunofluorescence. Other applications have not been tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Labeled with horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. HRP conjugates are sensitive to light.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free). Labeled with horseradish peroxidase (HRP).
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to a portion within aa 2-31 from the N-terminal region of human TOP1, conjugated to KLH.
Species sequence homologyHamster, mouse, rat
SpecificityRecognizes human TOP1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTOP1, DNA topoisomerase 1, DNA topoisomerase I


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