TREML1, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q86YW5

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Hu Mo

Accession #

NP_835468.1

Gene ID

340205

Gene #

TREML1

Shipping Temp

Blue Ice

Storage Temp

-20°C

TREML1, TLT1, Trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells-like protein 1

TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 [PubMed 12645956]; Barrow et al., 2004 [PubMed 15128762]).[supplied by OMIM].

Applications

Suitable for use in Western Blot and ELISA. Other applications not tested.

Recommended Dilutions

Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 215-241 in the C-terminal region of human TREML1.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A and peptide affinity chromatography.

Specificity

Recognizes human TREML1. Species Crossreactivity: mouse

References

1. Morales, J., et al. Blood Coagul. Fibrinolysis 21(3):229-236(2010). 2. Washington, A.V., et al. J. Clin. Invest. 119(6):1489-1501(2009). 3. Ford, J.W., et al. Curr. Opin. Immunol. 21(1):38-46(2009). 4. Nurden, A.T., et al. Thromb. Haemost. 100(1):45-51(2008). 5. Giomarelli, B., et al. Thromb. Haemost. 97(6):955-963(2007)

USBio References

No references available

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043205 Rabbit Anti-TREML1, CT (TREML1, TLT1, Trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells-like protein 1)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

TREML1, TLT1, Trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells-like protein 1

References

USBio References

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