TRPC4, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q9UBN4

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Accession #

NP_001129427.1; NP_001129428.1

Gene ID

7223

Gene #

TRPC4

Shipping Temp

Blue Ice

Storage Temp

-20°C

TRPC4, Short transient receptor potential channel 4, Trp-related protein 4

Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion.

Applications

Suitable for use in Western Blot, ELISA

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:100-500

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

TRPC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 811-840 amino acids from the C-terminal region of human TRPC4.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A affinity chromatography.

Specificity

Human

References

Mace, K.E., et al. J. Cell. Physiol. 225(2):444-453(2010)|von Spiczak, S., et al. Neuromolecular Med. 12(3):292-299(2010)|Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Schaefer, M., et al. J. Biol. Chem. 277(5):3752-3759(2002)

USBio References

No references available

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043286 Rabbit Anti-TRPC4, CT (TRPC4, Short transient receptor potential channel 4, Trp-related protein 4)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

TRPC4, Short transient receptor potential channel 4, Trp-related protein 4

References

USBio References

Conjugates

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