TTBK1, NT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q5TCY1

Isotype

IgG

Grade

Affinity Purified

Applications

E IHC WB

Crossreactivity

Hu Mo

Gene ID

84630

Gene #

TTBK1

Shipping Temp

Blue Ice

Storage Temp

-20°C

TTBK1, BDTK, KIAA1855, Tau-tubulin kinase 1, Brain-derived tau kinase

TTBK1 is Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.

Applications

Suitable for use in Western Blot, Immunohistochemistry

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 230-258 in the N-terminal region of human TTBK1.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A and peptide affinity chromatography

Specificity

Recognizes human TTBK1. Species Crossreactivity: mouse

References

1. Sato, S., et al. J. Neurosci. 28(53):14511-14521(2008) 2. Ewing, R.M., et al. Mol. Syst. Biol. 3:89 (2007) 3. Mungall, A.J., et al. Nature 425(6960):805-811(2003)