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You are here:Home » Antibodies » Abs to Thioredoxin » Anti -Txnip, ID (Txnip, Vdup1, Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1)

Anti -Txnip, ID (Txnip, Vdup1, Thioredoxin-interacting protein, Vitamin D3 up-regulated
protein 1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells.
Catalog #043481
ApplicationsSuitable for use in Western Blot. Other applications have not been tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to a region between corresponding to a portion of amino acids within aa116-145 from the Central region of mouse Txnip, conjugated to KLH. Species sequence homology: rat
SpecificityRecognizes mouse Txnip.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTxnip, Vdup1, Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1


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