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043610 Rabbit Anti-UNC45A, NT (UNC45A, SMAP1, Protein unc-45 homolog A, GCUNC-45, Smooth muscle cell-associated protein 1)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9H3U1
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_061141.2; NP_001034764.1
Gene ID
55898
Gene #
UNC45A
Shipping Temp
Blue Ice
Storage Temp
-20°C
UNC45A, SMAP1, Protein unc-45 homolog A, GCUNC-45, Smooth muscle cell-associated protein 1

UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
UNC45A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the N-terminal region of human UNC45A.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Chadli, A., et al. J. Biol. Chem. 283(15):9509-9512(2008)|Bazzaro, M., et al. Am. J. Pathol. 171(5):1640-1649(2007)|Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :|Olsen, J.V., et al. Cell 127(3):635-648(2006)|Olsen, J.V., et al. Cell 127(3):635-648(2006)
USBio References
No references available
Conjugates
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