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043622 Rabbit Anti-UNKL, NT (UNKL, C16orf28, ZC3H5L, ZC3HDC5L, Putative E3 ubiquitin-protein ligase UNKL, RING finger protein unkempt-like, Zinc finger CCCH domain-containing protein 5-like)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9H9P5
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001180317.1; NP_001032202.1
Gene ID
64718
Gene #
UNKL
Shipping Temp
Blue Ice
Storage Temp
-20°C

UNKL may participate in a protein complex showing an E3 ligase activity regulated by RAC1. Ubiquitination is directed towards itself and possibly other substrates, such as SMARCD2/BAF60b. Intrinsic E3 ligase activity has not been proven.

Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Optimal dilution determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within 1-30 amino acids from the N-terminal region of human UNKL. Species sequence homology: mouse
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human UNKL.
References
Lores, P., et al. FEBS J. 277(6):1453-1464(2010)|Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)|Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)|Martin, J., et al. Nature 432(7020):988-994(2004)|Venter, J.C., et al. Science 291(5507):1304-1351(2001)
USBio References
No references available
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