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You are here:Home » Antibodies » Abs to Tetraspanin » Anti -UPK1B, ID (UPK1B, TSPAN20, Uroplakin-1b, Tetraspanin-20, Uroplakin Ib) (APC)

Anti -UPK1B, ID (UPK1B, TSPAN20, Uroplakin-1b, Tetraspanin-20, Uroplakin Ib) (APC)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH FC
UPK1B is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.
Catalog #043634-APC
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Flow Cytometry. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Allophycocyanin (APC).
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to a portion within aa159-188, central region of human UPK1B, conjugated to KLH. Cellular Localization: Mmebrane; Multi-pass membrane protein
SpecificityRecognizes human UPK1B at ~29kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesUPK1B, TSPAN20, Uroplakin-1b, Tetraspanin-20, Uroplakin Ib


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