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043650 Rabbit Anti-USF1, ID (USF1, BHLHB11, USF, Upstream stimulatory factor 1, Class B basic helix-loop-helix protein 11, Major late transcription factor 1)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
P22415
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IF IHC WB
Crossreactivity
Hu Mo
Accession #
NP_009053.1
Gene ID
7391
Gene #
USF1
Shipping Temp
Blue Ice
Storage Temp
-20°C
USF1, BHLHB11, USF, Upstream stimulatory factor 1, Class B basic helix-loop-helix protein 11, Major late transcription factor 1

This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Indirect Flow Cytometry, ELISA. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Immunofluorescence: 1:10-1:50 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 174-201 in the central region of human USF1. Species Sequence Homology: bovine.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human USF1. Species Crossreactivity: mouse.
References
1. Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010). 2. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). 3. Bussiere, F.I., et al. Cell. Microbiol. 12(8):1124-1133(2010). 4. Naukkarinen, J., et al. Circ Cardiovasc Genet 2(5):522-529(2009). 5. Singmann, P., et al. Obes Facts 2(4):235-242(2009)
USBio References
No references available
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