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You are here:Home » Antibodies » Abs to Wnt Proteins » Anti -WNT3, ID (WNT3, INT4, Proto-oncogene Wnt-3, Proto-oncogene Int-4 homolog)

Anti -WNT3, ID (WNT3, INT4, Proto-oncogene Wnt-3, Proto-oncogene Int-4 homolog)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Catalog #043890
ApplicationsSuitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 155-184 in the central region of human WNT3, UniProt Accession #P56703.
Species sequence homologyChicken, mouse, xenopus
SpecificityRecognizes human WNT3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesWNT3, INT4, Proto-oncogene Wnt-3, Proto-oncogene Int-4 homolog


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