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043997 Rabbit Anti-ZBTB32, NT (ZBTB32, FAZF, TZFP, ZNF538, Zinc finger and BTB domain-containing protein 32, FANCC-interacting protein, Fanconi anemia zinc finger protein, Testis zinc finger protein, Zinc finger protein 538)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9Y2Y4
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_055198.1
Gene ID
27033
Gene #
ZBTB32
Shipping Temp
Blue Ice
Storage Temp
-20°C
ZBTB32, FAZF, TZFP, ZNF538, Zinc finger and BTB domain-containing protein 32, FANCC-interacting protein, Fanconi anemia zinc finger protein, Testis zinc finger protein, Zinc finger protein 538

ZBTB32 is a DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells (By similarity).

Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 96-125 in the N-terminal region of human ZBTB32.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human ZBTB32.
References
1. Stogios, P.J., et al. J. Mol. Biol. 400(5):983-997(2010) 2. Kaufmann, S., et al. J. Gen. Virol. 91 (PT 6), 1494-1502 (2010) : 3. Xin, X., et al. Genome Res. 19(7):1262-1269(2009) 4. Cohn, M.A., et al. Mol. Cell 28(5):786-797(2007) 5. Ikeda, R., et al. J. Cell. Biochem. 101(1):147-154(2007)
USBio References
No references available
Conjugates
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