ZEB2, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

O60315

Isotype

IgG

Grade

Affinity Purified

Applications

E FC WB

Crossreactivity

Accession #

NP_055610.1; NP_001165124.1

Gene ID

9839

Gene #

ZEB2

Shipping Temp

Blue Ice

Storage Temp

-20°C

ZEB2, KIAA0569, SIP1, ZFHX1B, ZFX1B, Zinc finger E-box-binding homeobox 2, Smad-interacting protein 1, Zinc finger homeobox protein 1b

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.

Applications

Suitable for use in Western Blot, Indirect Flow Cytometry and ELISA. Other applications have not been tested.

Recommended Dilutions

Western Blot: 1:2000 Flow Cytometry (Indirect): 1:10-1:50 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1078-1105 in the C-terminal region of human ZEB2. Species Sequence Homology: mouse

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide

Purity

Purified by Protein A and peptide affinity chromatography

Specificity

Recognizes human ZEB2.

References

1. Kumar, P.A., et al. J. Biol. Chem. 285(41):31148-31156(2010). 2. Li, A., et al. Cancer Res. 70(13):5226-5237(2010). 3. Ohashi, S., et al. Cancer Res. 70(10):4174-4184(2010). 4. Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010). 5. Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010)

USBio References

No references available

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044055 Rabbit Anti-ZEB2, CT (ZEB2, KIAA0569, SIP1, ZFHX1B, ZFX1B, Zinc finger E-box-binding homeobox 2, Smad-interacting protein 1, Zinc finger homeobox protein 1b)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

ZEB2, KIAA0569, SIP1, ZFHX1B, ZFX1B, Zinc finger E-box-binding homeobox 2, Smad-interacting protein 1, Zinc finger homeobox protein 1b

References

USBio References

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