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You are here:Home » Molecular Biology » MB-Infectious Disease » ACE2:Fc, Recombinant, Human (SARS Receptor, Angiotensin-converting Enzyme 2, ACEH)

ACE2:Fc, Recombinant, Human (SARS Receptor, Angiotensin-converting Enzyme 2, ACEH)


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ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.
Catalog #044454
Biological ActivityHydrolysis of a fluorescent peptide substrate, Mca-Y-V-A-D-A-P-K(Dnp)-OH.
SequenceSignal peptide sequence and the extracellular domain of human ACE2 (aa 1-740) are fused at the C-terminus to the Fc portion of human IgG1.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
Molecular Weight~120kD (SDS-PAGE)
SourceHuman, HEK 293 cells
Purity>95% (SDS-PAGE)
FormSupplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSARS Receptor, Angiotensin-converting Enzyme 2, ACEH

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