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You are here:Home » Antibodies » Abs to Interferon » Anti -AIM2 (Interferon-inducible Protein AIM2, Absent in Melanoma 2)

Anti -AIM2 (Interferon-inducible Protein AIM2, Absent in Melanoma 2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Highly Purified B IC
AIM2 is a strong candidate as a tumor suppressor as it is a member of the HIN-200 (hemopoietic interferon-inducible, nuclear proteins containing a 200 amino acid repeat) family of proteins that have been shown to regulate cell growth and survival. The HIN-200 family of proteins consists of four members in human, IFI 16, MNDA, AIM2 and IFIXl. Recently it has been reported that AIM2 is a receptor for cytosolic dsDNA, which forms a novel inflammasome complex with ASC to activate caspase-1-mediated processing of IL-1beta.
Catalog #044493
ApplicationsSuitable for use in Immunocytochemistry, Western Blot
Recommended DilutionOptimal dilutions to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No3B10
HostMouse
SourceHuman
Concentration1mg/ml
FormSupplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
Purity>95% (SDS-PAGE)
ImmunogenHuman AIM2 (aa 1-186).
SpecificityRecognizes human AIM2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesInterferon-inducible Protein AIM2, Absent in Melanoma 2


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