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You are here:Home » Molecular Biology » MB-Apoptosis » Annexin V, Recombinant, Human (Annexin A5, Endonexin II, Lipocortin V, Placental Anticoagulant Protein I, Calphobindin I, Vascular Anticoagulant-alpha)

Annexin V, Recombinant, Human (Annexin A5, Endonexin II, Lipocortin V, Placental
Anticoagulant Protein I, Calphobindin I, Vascular Anticoagulant-alpha)

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Specifications

Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
Catalog #044558
SequenceRecombinant human annexin V fused to a GST-tag.
Storage and StabilityShort-term Storage: +4°C
Long-term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. Reconstituted solutions can be kept at 4°C under sterile conditions for one week or should be frozen in aliquots at -20°C.
Molecular Weight~52kD (SDS-PAGE)
SourceHuman, E. coli
Purity>95% (SDS-PAGE)
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
SpecificityBinds to phosphatidylserine (PS).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAnnexin A5, Endonexin II, Lipocortin V, Placental Anticoagulant Protein I, Calphobindin I, Vascular Anticoagulant-alpha


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